Table of Contents

Contact Us

Department of Animal Sciences
The Robert H. Smith Faculty
of Agricultural, Food & Environment

The Hebrew University of Jerusalem.

P.O. Box 12, Rehovot 76100, Israel
Phone: +972-(0)8-9489119;
Fax: +972-(0)8-9465763;
Yael Lewitus, Department's Secretary

List of Publications

Chapters in Collections

  • Nebel RL, Jones CM and Roth Z (2011) “Reproduction, events and management: Mating management: Detection of oestrus”. Fuquay JW, fox PF and McSweeney PLH (eds.) Encyclopedia of Dairy Sciences, Second Edition, vol. 4, pp. 461-466. San Diego: Academic Press.

Review Articles

  1. Wolfenson D, Roth Z and Meidan R (2000) Impaired reproduction in heat-stressed cattle: basic and applied aspects. Animal Reproduction Science 60-61, 535-547 (Invited review).
  2. Roth Z (2008) Heat stress, the follicle and its enclosed oocyte: mechanism and potential strategies to improve fertility in heat-stressed cows. Reproduction in Domestic Animal, 43 Suppl. 2:238-244 (Invited review).
  3. Wolfenson D, Roth Z, Lavon Y, and Leitner G (2014) Effects of mastitis on ovarian function and fertility in dairy cows. In: Juengel, J.L., Miyamoto, A., Reynolds, L.P., Smith, M.F., and Webb, R., eds., Reproduction in Domestic Ruminants VIII. Context Publishing, Packington Leicestershire, pp 431-443; (Invited review).
  4. Roth Z (2014) Effects of heat stress on ovarian functions and embryonic development. In: Juengel, J.L., Miyamoto, A., Reynolds, L.P., Smith, M.F., and Webb, R., eds., Reproduction in Domestic Ruminants VIII. Context Publishing, Packington Leicestershire, pp 193-208 (Invited review).
  5. Roth Z (2015) Cellular and molecular mechanisms of heat stress related to bovine ovarian function, Journal of Animal Science 93(5):2034-44 (Invited review).
  6. Roth Z and Wolfenson D (2016) Comparison the effects of mastitis and heat stress on ovarian function in lactating cow: basic and applied aspects. Domestic Animal Endocrinology Domestic Animal Endocrinology 56 S218–S227 (Invited review).
  7. Roth Z (2017) Effect of heat stress on reproduction in dairy cows - insights into the cellular and molecular responses of the oocyte. Annu. Rev. Anim. Biosci. 2017. 5:151-170 (Invited review).
  8. Roth Z (2017) Reduction in oocyte developmental competence by stress is associated with alterations in mitochondrial function [ADSA annual meeting] Invited review

Mini Review

  1. Arav A and Roth Z (2008) Do chilling injury and heat stress share the same mechanism of injury in oocytes? Molecular and Cellular Endocrinology 30; 282 (1-2):150-152; Special issue for the second French-Israeli symposium Tel-Aviv, Israel.
  2. Qi Meiyu, Roth Z, and Liu Di (2012) Insulin-like Growth Factor-I (IGF-I) in Reproduction System of Female Bovine. Journal of Northeast Agricultural University, China (English Edition) Vol. 18 4:84-87.
  3. Roth Z (2012) Hormonal treatments to improve fertility in high lactating cows during the summer and autumn-basic and applied studies XVI Curso Novos Enfoques Producaoe Reproducao de Bovinas
  4. Roth Z (2014) Insights into the cellular and molecular responses of bovine oocytes and embryos to elevated temperature. Proceeding for the 30th scientific meeting of the European Embryo Transfer Association (AETE) Dresden, Germany.
  5. Roth Z (2017) Cooling management and hormonal treatments to improve fertility in high lactating cows during the summer and autumn. Proceeding for the Veterinary Symposia, Girne, Kuzey Kibris Turk Cumhuriyeti, 2017.


  1. Roth Z, Meidan R, Braw-Tal R and Wolfenson D (2000) Immediate and delayed effects of heat stress on follicular development and its association with plasma FSH and inhibin concentration in cows. Journal of Reproduction and Fertility, 120, 83-90.
  2. Levy N, Kobayashi S, Roth Z, Wolfenson DC, Miyamoto AC and Meidan RPI (2000) Administration of prostaglandin F2α during the early bovine luteal phase dose not alter the expression of ET-1 and its type A receptor: A possible cause for corpus luteum refractoriness. Biology of Reproduction, 63, 377-382.
  3. Roth Z, Meidan R, Braw-Tal R, Shaham-Albalancy A and Wolfenson D(2001) Delayed effect of heat stress on steroidogenesis in bovine medium-size and preovulatory follicles. Reproduction, 121, 745-751.
  4. Roth Z, Arav A, Bor A, Zeron Y, Braw-Tal R and Wolfenson D (2001) Improvement of quality of oocyte collected in the autumn by enhanced removal of impaired follicles from previously heat-stressed cows. Reproduction, 122, 737-744.
  5. Roth Z, Arav A, Bor A, Zeron Y, Braw-Tal R and Wolfenson D (2002) Effect of treatment with FSH or bST on the quality of oocytes aspirated in the autumn from previously heat-stressed cows. Journal of Dairy Science, 85, 1398-1405.
  6. Wolfenson D, Inbar G, Roth Z, Kaim M, Bloch A and Braw-Tal R (2004) Follicular dynamic and concentrations of steroids and gonadotropins in lactating cows and nulliparous heifers.Theriogenology, 15, 1042-1055.
  7. Roth Z, Bor A, Braw-Tal R and Wolfenson D (2004) Carry-over effect of summer thermal stress on characteristics of the preovulatory follicle of lactating cows. Journal of Thermal Biology, 29, 681-685.
  8. Roth Z and Hansen PJ (2004) Involvement of apoptosis in heat-induced disruption of competence of bovine oocyte. Biology of Reproduction, 71, 1898-1906.
  9. Roth Z and Hansen PJ (2004) Sphingosine-1-Phosphate protects cultured bovine oocytes from physiologically-relevant thermal stress. Biology of Reproduction, 71, 2072-2078.
  10. Roth Z and Hansen PJ (2005) Disruption of nuclear maturation and rearrangement of cytoskeletal elements in bovine oocytes exposed to heat shock during maturation. Reproduction, 129, 235-244.
  11. Braw-Tal R and Roth Z (2005) Gene expression for LH receptor, 17α-hydroxylase and StAR in the theca interna of preantral and early antral follicles in the bovine ovary. Reproduction, 129, 453-461.
  12. Bloch A, Folman Y, Kaim M, Roth Z, Braw-Tal R and Wolfenson D (2006) Endocrine alteration associated with extended time interval between estrus and ovulation in high- yield dairy cows. Journal of Dairy Science, 89, 4694-4702.
  13. Argov N, Sklan D, Zeron Y and Roth Z (2007) Association between seasonal changes in fatty-acid composition expression of VLDL receptor and bovine sperm quality. Theriogenology, 67, 878-885.
  14. Aroyo A, Yavin S, Arav A and Roth Z (2007) Maternal hyperthermia disrupts developmental competence of follicle-enclosed oocytes: In vivo and ex vivo studies in mice. Theriogenology, 67, 1013-1061.
  15. Roth Z, Inbar G and Arav A (2008) Comparison of oocyte developmental competence and follicular steroid content of nulliparous heifers and cows at different stages of lactation. Theriogenology, 69(8):932-939.
  16. Jousan FD, de Castro e Paula LA, Brad AM, Roth Z and Hansen PJ (2008) Relationship between Group II Caspase Activity of Bovine Preimplantation Embryos and Capacity for Hatching. Journal of Reproduction and Development, 54(3):217-220.
  17. Roth Z, Aroyo A, Saar Y and Arav A (2008) The antioxidant epigallocatechin gallate (EGCG) moderates the deleterious effect of maternal hyperthermia on follicle-enclosed oocyte. Theriogenology, 70(6): 887-897.
  18. Arav A, Aroyo A, Yavin S and Roth Z (2008) Prediction of embryonic developmental competence by time-lapse system and 'shortest half' analysis; on web Reproductive BioMedicine Online; 17 (5) 669-675.
  19. Yavin S, Aroyo A, Roth Z and Arav A (2009) Embryo cryopreservation in the presence of low concentration of vitrification solution with sealed pulled straws in liquid nitrogen slush. Human Reproduction, 24 (4) 797-804.
  20. Braw-Tal R, Pen S and Roth Z (2009) Ovarian cyst in high-yield dairy cows. Theriogenology, 72:690-698.
  21. Gendelman M, Aroyo A, Yavin and Roth Z (2010) Seasonal effects on gene expression, cleavage timing, and developmental competence of bovine preimplantation embryos, Reproduction, 140:73-82.
  22. Friedman E, Glick G, Lavon Y and Roth Z (2010) Effects of low-dose FSH administration on follicular dynamics and preovulatory follicle characteristics in dairy cows during the summer. Domestic Animal Endocrinology, 39: 106-115.
  23. Shcherbina Y, Roth Z and Nussinovitch A (2010) Physical properties of gum karaya-starch-essential oil patches AAPS PharmSciTech, PMID: 20711695.
  24. Friedman E, Voet H, Reznikov D, Dagoni I and Roth Z (2011) Induction of successive follicular waves by GnRH and PGF2α to improve fertility of lactating cows during the summer and autumn. Journal of Dairy Science, 94: 2393–2402.
  25. Kalo D and Roth Z (2011) Involvement of the sphingolipid ceramide in heat-induced apoptosis in bovine oocytes. Reproduction, Fertility and Development, 23: 876-888.
  26. Gendelman M and Roth Z (2012) Seasonal effect on germinal vesicle-stage bovine oocytes is further expressed by alteration in transcript levels in the developing embryos associated with reduced developmental competence. Biology of Reproduction, 86 (1) 8, 1-9.
  27. Orgal S, Zeron Y, Elior N, Biran D, Fridman E, Druker S and Roth Z (2012) Season-induced changes in bovine sperm motility following freeze-thaw procedure, Journal of Reproduction and Development, Vol. 58 (2012) No. 2 p. 212-218.
  28. Roth Z, Biran D, Lavon Y, Dafni I, Yakobi S and Braw-Tal R (2012) Endocrine milieu and developmental dynamics of ovarian cysts and persistent follicles in postpartum dairy cows. Journal of Dairy Science, 95:1729-1737.
  29. Friedman E, Roth Z, Voet H, Lavon Y and Wolfenson D (2012) Progesterone supplementation post-insemination improves fertility of cooled dairy cows during the summer Journal of Dairy Science, 95:3092–3099.
  30. M Gendelman and Z Roth (2012) In-vivo versus in-vitro models for studying the effects of elevated temperature on the GV-stage oocyte, subsequent developmental competence and gene expression. Animal Reproduction Science 134; 125-134.
  31. D Grossman, D Kalo, M Gendelman and Z Roth (2012) Effect of di-(2-ethylhexyl) phthalate and mono-(2-ethylhexyl) phthalate on in- vitro developmental competence of bovine oocytes. Cell Biology and Toxicology 28:383-396.
  32. M Gendelman and Z Roth (2012) Incorporation of Coenzyme Q10 into Bovine Oocytes Improves Mitochondrial Features and Alleviates the Effects of Summer Thermal Stress on Developmental Competence. Biology of Reproduction 87(5); 118, 1-12.
  33. N Argov-Argaman, K Mahgrefthe, Y Zeron, and Z Roth (2013) Season-induced variation in lipid composition is associated with semen quality in Holstein bulls. Reproduction 145, 479-489.
  34. N Argov-Argaman, K Mahgrefthe, Y Zeron, Z Roth(2013) Variation in lipid profiles within semen compartments—the bovine model of aging. Thriogenology 80:712-721.
  35. Roth Z, Dvir A, Kalo D, Lavon Y, Krifucks O, Wolfenson D, Leitner G (2013) Naturally occurring mastitis disrupts developmental competence of bovine oocytes. Journal of Dairy Science96:6499-505.
  36.  Asaf S, Leitner G, Furman O, Lavon Y, Kalo D, Wolfenson D, Roth Z (2014) Effects of Escherichia coli- and Staphylococcus aureus-induced mastitis in lactating cows on oocyte developmental competence. Reproduction 147:33-43.
  37. Meiyu Qi, Liu Di and Roth Z (2014) IGF-I slightly improves nuclear maturation and cleavage rate of bovine oocytes exposed to acute heat shock in-vitro. Zygote, doi:
  38. Furman O, Leitner G, Roth Z, Lavon Y, Jacoby S, and Wolfenson (2014) Experimental model of toxin-induced subclinical mastitis and its effect on disruption of follicular function in cows. Theriogenology, 82:1165-1172.
  39. Friedman E, Voet H, Reznikov D, Wolfenson D and Roth Z (2014) Hormonal treatment before and after artificial insemination differentially improves fertility in subpopulations of dairy cows during the summer and autumn Journal of Dairy Science, 97 :7465-7475.
  40. Ying L, Kalo D, Zeron Y, Roth Z (2014) Progressive motility—a potential predictive parameter for semen fertilization capacity in bovines Zygote, doi:10.1017/S0967199414000720.
  41. Moallem U, Neta N, Zeron Y, Zachut M and Roth Z (2015) Omega-3 fatty acids dietary from flaxseed or fish oil sources differentially alters fatty acid composition and characteristics of fresh and frozen bulls’ semen Theriogenology, 87: 1110-11120.
  42. Roth Z, Asaf S, Furman O, Lavon Y, Kalo D, Wolfenson D, Leitner G (2015) Subclinical mastitis disrupts oocyte cytoplasmic maturation in association with reduced developmental competence and impaired gene expression in preimplantation bovine embryos. Reproduction Fertility and development, doi: 10.1071/RD14431.
  43. Kalo D and Roth Z(2015) Effects of mono(2-ethylhexyl)phthalate on cytoplasmic maturation of oocytes- the bovine model. Reproductive Toxicology, doi: 10.1016/j.reprotox.2015.04.007.
  44. Biran D, Braw-Tal R, Gendelman M, Lavon Y, Roth Z (2015) ACTH administration during formation of preovulatory follicles impairs steroidogenesis and angiogenesis in association with ovulation failure in lactating cows. Domestic Animal Endocrinology, 53: 52–59.
  45. Kalo D, Hadas R, Furman O, Ben-Ari J, Maor Y, Patterson D, Tomey C, Roth Z(2015) Carryover effects of acute DEHP exposure on ovarian function and oocyte developmental competence in lactating cows. PlosOne, doi:10.1371/journal.pone. 0130896.  
  46. Malama E, Zeron Y, Janett F, Siuda M, Roth Z, Bollwein H (2016) Seasonal variation in the quality of frozen-thawed semen collected from Holstein-Friesian bulls under subtropical conditions. Theriogenology ;87:79-90.
  47. Sofia M. Ortega, Nathalia Rocha-Frigoni , Gisele Zoccal Mingoti, Zvi Roth and Peter J. Hansen (2016) Modification of embryonic resistance to heat shock in cattle by melatonin and genetic variation in HSPA1L. Journal of Dairy Science,  99 (11 ); 9152-9164.
  48. Komsky-Elbaz A and Roth Z (2016) Effect of the herbicide Atrazine and its metabolite diaminochlorotriazine (DACT) on bovine sperm quality and fertilization competence.  Reproductive Toxicology, 67, 15-25.
  49. Kalo D and Roth Z (2017) In vitro animal model to study the effect of residual concentration of Mono-(2-ethylhexyl) phthalate in follicular fluid on oocyte developmental competence. Toxicology 377, 38–48.
  50. Roth Z, Shcherbina Y and Nussinovitch A (2017) Transdermal Delivery of Lavandula angustifolia and Valencia Orange Essential Oils Using Gum-karaya Patches Med. Aromat. Plants (Los Angles) DOI: 10.4172/2167-0412.1000291.
  51. Komsky-Elbaz A, Sktsier M, Roth Z. 2017. Aflatoxin B1 impairs sperm quality sperm and fertilization competence. Toxicology [Epub ahead of print].