Research

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Zehava Uni lab

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Department of Animal Sciences
The Robert H. Smith Faculty
of Agricultural, Food & Environment

The Hebrew University of Jerusalem.

P.O. Box 12, Rehovot 76100, Israel
Phone: +972-(0)8-9489119;
Fax: +972-(0)8-9465763;
Yael Lewitus, Department's Secretary
e-mail: yaellew@savion.huji.ac.il

Teaching and research activities of the department of animal science concern the processes of molecular and cellular pathways in cells and organs and their role in the functions, reproduction, development and the behavior of living farm animals (fish, poultry, bovine)

The agenda covers a broad range of specialized disciplines including cell biology, molecular biology, genomics, endocrinology, immunology, microbiology, nutrition and also behavior.

Fish

Genetics

Dr. Lior David

Research is focused on genetics and evolution of complex traits. For that, state-of-the-art genetic, genomic and computational tools are applied to address genetic questions using the yeast as a basic model and fish as non-model organisms. The research interests in yeast include studying the genetic basis of complex traits and the evolution of gene regulation networks. In fish, Dr. David is studying the genetics of infectious disease resistance and of sex determination. The group studies also the genetics of natural freshwater fish populations to address ecological and conservation risks. The insights from his basic research are used to breed for genetically improved fish strains and to solve significant practical problems impeding fish aquaculture.

Reproduction and Endocrinology

Prof. Berta Levavi-Sivan

Research is in the area of reproduction and endocrinology in fish. This includes various levels as the mechanisms underlying hypothalamic regulation in fish; puberty in fish; Novel neuropeptides and their effect on metabolism and reproduction; The relationship between growth and reproduction in fish; Production of recombinant gonadotropins using the expression system of Pichia pastoris; Sex inversion in fish; Study the mechanisms underlying FSH and LH release using transgenic tilapia and zebrafish.

Aquaculture and water quality

Prof. Jaap van Rijn

Research is in the area of aquaculture: Aquatic microbiology, Biological transformation of N, P, C and S in aquatic systems and Water quality control in fish culture systems

 

Poultry 

Nutrition and the digestive tract

Prof. Zehava Uni

Research is focused on the functional development of the chicken digestive system and the influence of specific nutrients on the integrity and functional capability of the gut epithelium. The goal of this research is to improved efficiency of poultry nutrition. Research projects molecular, morphological and functional changes during the development of the intestine in chicken; Methods of accelerating the gut development in poultry – in ovo feeding/  feeding before hatch; Modulating intestinal microflora by feed additives; Yolk sac tissue development and functionality during incubation period; Bitter Taste Perception in the chicken digestive tract;

Immunology

Prof. Aharon Friedman

Research activities is to understand cellular and molecular mechanisms governing the interaction between the gastrointestinal tract and the immune response. The research focus on the development of the gut-associated immune system (GALT) in omnivorous birds: influences of gastro-intestinal development, bacterial colonization and nutrition; Immune related function s of the intestinal epithelial cell (IEC) and development of tolerance or response following intestinal (oral or rectal) intake of antigen.

Gut bacteriology

Dr. Erez Mills

The complex community of microbes residing in our gut, also known as the gut microbiota, is currently seen as an organ by its own right. The gut microbiota provides multiple functions for its host, such as protection from gut pathogens and the conversion of indigestible plant material to compounds the host can absorb and utilize. Currently, the lab is dedicated to the study of the commensal and pathogenic bacterial components of the chicken gut microbiota, and their interactions with each other and the host. A secondary goal is to utilize our knowledge to redesign the gut microbiota to increase animal wellbeing and industrial efficiency.

  • Muscle

Prof. Halevy Orna

Research activities is in the field of skeletal muscle repair; Regulation of proliferation and differentiation of skeletal muscle cells and Environmental and nutritional effects on muscle growth and meat production in chicken

Reproduction

Prof. Israel Rozenboim

Area of research focuses on studying the mechanism by which light affect reproduction and performance in poultry (hens and roosters).   The research topics is focusing on manipulating growth of meat type birds by monochromatic photo-stimulation; Embryonic photo-stimulation; reproductive failure associated with heat stress in turkey hens and the relationship between the eye and the brain in controlling reproductive activities of birds.

Bovine & ovine  

Nutrition and feedstuff

Prof. Sameer J. Mabjeesh

Research is focused on nutrition and feedstuffs for small ruminants including the development of industrial by-products as feedstuffs for ruminants; Halophytes as roughage source in ruminants’ ration; Amino acids metabolism at the mammary gland, protein synthesis and secretion; Absorption and partition of nutrients for milk production; Flavors and their role in ruminant nutrition and feed intake 

Milk

Dr. Nurit Argov

Research is focused on milk fat globule. Research projects are concentrating on  dietary means to control milk lipid composition with the goal to increase content of bioactive molecules in the milk; Revealing the metabolic-biochemical pathways regulating milk fat content and composition focusing on milk fat globule size; Study how local breeds of dairy animals utilize local vegetation.

Reproduction

Prof. Meidan Rina

Research activities is in the area of dairy cow’s pregnancy focusing on the corpus luteum endocrine gland. Mechanisms, in mammalians, controlling the demise of the corpus luteum; Angiogenesis during corpus luteum development; transcriptional regulation and molecular forms of of ovarian endothelin1 expression

Prof. Roth Zvi

Area of research focuses on studying the mechanism by which various stresses affect reproductive performance in dairy cows and in bull’s sperm. Stressors includes thermal stress, oxidative stress, environmental toxicants, pathogenic stress, and endocrine disruptors. Research topics are  examination of the cellular and molecular mechanisms underlying disruptions in gametes  (oocytes and sperm);  Evaluation of early embryonic development; Use of complementary experimental models (in-vivo, in-vitro and ex-vivo); establishment of  new approaches  and novel strategies that could potentially have practical applications in the dairy.

Stem cells

Dr. Sharon Schlesinger

Research is in the area of epigenetic regulation of Stem Cells. The work is dealing with fundamental questions of genomic regulation and developmental biology, and applying the recent progress of the field to domesticated animals. Research topics are retroviral silencing and histone dynamics in embryonic stem cells, DNA methylation in the developing human gut and immunomodulatory effect of mesenchymal stem cells in the mammary gland and uterine of the cow.  

 

Behavior

Dr Oren Forkosh

The lab for happiness and well-being; studying the positive psychology in animals (and some in humans). Development of tools to track the movement and behavior of animals, using machine learning and AI to analyze the data and construct mathematical models in order to understand things such as personality, social behavior, learning, and so on.