Dr. Sharon Elizur-Schlesinger

In the Schlesinger lab, we study epigenetic reprogramming following fertilization. In particular, we are interested in the process leading to the formation of heterochromatin de novo and silencing of transposable elements and retroviruses. We use embryonic stem (ES) cells from mice and from farm animals to get a deeper understanding of the general characteristics of pluripotency in all mammalian cells.

 

Research interests:

 

The histone variant H3.3 and retroviral silencing Mouse Embryonic Stem Cells (ESC) and retroviral silencing by the Smarcad1 chromatin remodeler Bovine induced pluripotent stem cells Bovine Mesenchymal Stem Cells response to heat ( Transposable elements regulation in response to viral infection

The histone variant
H3.3 and retroviral silencing

Mouse Embryonic Stem Cells (ESC) and retroviral silencing
by the Smarcad1
chromatin remodeler

Bovine induced
pluripotent stem cells

Bovine Mesenchymal Stem Cells
response to heat

Transposable elements
regulation
in response to viral infection