Dr. Sharon Schlesinger

In the Shlez lab, we study the epigenetic reprogramming following fertilization. In particular, we are interested in the process leading to the formation of heterochromatin de novo and silencing of transposable elements and endogenous retroviruses. We use embryonic stem (ES) cells from mice and from farm animals to get a deeper understanding of the general characteristics of pluripotency in all mammalian cells.



The Schlesinger lab – research interests:


Epigenetic regulation in embryonic stem cells


Retroviral silencing in embryonic stem cells


Bovine pluripotent stem cells


Chronic inflammation alters DNA methylation patterns in the human gut


Generation and characterization of Mesenchymal Stem Cells for use in cell therapy