Prof. Lior David
Associate Professor
Vigevani Senior Lectureship in Animal Sciences
Animal Sciences, Room: 002
Genetics and evolution of complex traits in fish and yeast.
Table of Contents
Contact Us
Department of Animal Sciences
The Robert H. Smith Faculty
of Agricultural, Food & Environment,
The Hebrew University of Jerusalem.
Herzl 229, Rehovot 7610001, Israel
Phone: +972-(0)8-9489119;
Fax: +972-(0)8-9465763;
Yael Lewitus, Department's Secretary
e-mail: yaellew@savion.huji.ac.il
Lab members
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Rachel Shapira, Ph.D |
My ph.D. studies focused on characterized and dissecting the genetic bases of complex quantitative traits, using different aspects of research like association studies, linkage analysis, sequential elimination of different effects on the trait and etc. In my studies I generated 120 hybrids collection of 16 divergent strains, backcrosses, F1 and F2 populations and etc. High temperature growth of sacchromyces cerevisiae- budding yeast is a quantitative, heterotic trait which I used as a trait model. In my work I identified seven different genes inside a mild effect locus contribute the trait and another five different genes with an over-dominant mode of inheritance affecting heterosis (hybrid vigor), which has a great importance in food production fields.
Publications: |
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Roni Tadmor |
My work is focused on the genetics of complex traits in the common carp (Cyprinus carpio), a fish of high economic value and fascinating genetics. The common carp has a tetraploid genome, due to recent (12 MYA) genome duplication. The first part of my research aims to construct a genetic map that will capture the complex nature of carp genime and describe the relations between the paralogic areas that evolved after duplication. In another part of my work, I am working on the genetic basis of several complex traits, especially for resistance to CyHV-3 virus that causes mortality in aquaculture production of common carp. The research I am involved in combines practicable implementations such as breeding CvHV-3 resistant of common carp, as well as evolutionary aspects of the nature of duplicated genomes and the impact of duplicated genes on speciation. |
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Tomer Borovski |
In my master project I am characterized the genetic variation and the population structure of Amnon Galilee (Sarotherodongalilaeus) in the Kinneret, Israel. We estimate the genetic diversity of the population, and compare it among others to population in Africa and try to understand its implications on the stability of the population. We are trying to develop different ways to preserve the genetic diversity, as increasing the efficiency of the annual populating to the Sea of Galilee and the establishment of a data base for identifying genetic Kinneret fish and freshwater species in Israel. |
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Tal Levy |
Our laboratory has been studying epigenetic evolutionary in which we expose yeast cells (Sacchromyces cerevisiae-budding yeast) to environmental conditions they did not encountered before. Cells that succeed with the adaptation process inherit the adaptation phenotype to their progeny. We examine and want to understand that changes (genetic and/or epigenetic) accompanying this adaptation process in the cells. In my master's project I examine the hypothesis that there are some epigenetic factors that influence and contribute to the process of adaptation to new environmental conditions and characterize them. |
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Efrat Asulin |
In my research I am dealing with enhancement of resistant of common carp strains to KHV (Koi Herpes Virus) virus, by genetic tools. KHV is a deadly virus to these species and cause enormous damage to the aquaculture industry. The main method I am using in my project is the development of SNP markers on the genes that are linkage to the survival phenotype. Simultaneously I am working for better understanding of the resistance mechanism and the differences between susceptible and survival fishes in spreading the virus. All these will enable better genetic selection for resistant fishes in low cost and high effectiveness |
